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In these groups, hermaphroditism is a normal condition, enabling a form of sexual reproduction in which either partner can act as the "female" or "male".

The word intersex has come into preferred usage for humans, since the word hermaphrodite is considered to be misleading and stigmatizing, Since the estimated total number of animal species is 8.6 million, the percentage of animal species that are hermaphroditic is about 0.7%.

According to Ovid, he fused with the nymph Salmacis resulting in one individual possessing physical traits of male and female sexes; Alexander ab Alexandro stated, using the term hermaphrodite, that the people who bore the sexes of both man and woman were regarded by the Athenians and the Romans as monsters, and thrown into the sea at Athens and into the Tiber at Rome.

This contrasts simultaneous hermaphrodites, in which an individual may possess fully functional male and female gonads.

Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genome (KEGG) pathway enrichment analysis showed transcription factors, flower development, histone H3-K9 methylation, and plant hormone signal transduction were among the most significantly enriched GO terms and KEGG pathways.

Small RNA analysis was also performed on the pistils from normal male and the male-to-hermaphrodite sex reversal flowers.